My wife Linda and I just got back from 5 days in Canmore where we attended a David Taylor (go to his site, you won't be disappointed) workshop.
If you ever get a chance to attend a David Taylor workshop do it! David teaches his method of hand applique. He appliques with his quilt flat on a table so that the resulting quilt lies perfectly flat.
Hand applique is something I've never done. But now it's something I want to do again.